Online Contents
Cover
Title
Copyright
Contents
Figures
Tables
Foreword
Acknowledgements
Chapter 1 — An Industrial Perspective 1
  1.1 Products 2
  1.2 Process Characteristics 8
  1.3 Measurement and Control Characteristics 18
Chapter 2 — Flow, Level, Pressure, and Temperature Measurements 31
  2.1 Flow Measurements 32
  2.2 Level Measurements 35
  2.3 Pressure Measurements 36
  2.4 Temperature Measurements 36
Chapter 3 — REDOX and pH Measurements 39
  3.1 REDOX Measurements 39
  3.2 pH Measurement 44
  3.3 Electrode Installation 60
  3.4 Electrode Sterilization 62
Chapter 4 — Dissolved Oxygen and Carbon Dioxide Measurements 65
  4.1 Dissolved Oxygen Measurement 66
  4.2 Dissolved Carbon Dioxide Measurement 71
Chapter 5 — Composition Measurements 77
  5.1 Biosensors 78
  5.2 CHEMFETs and ISFETs 81
  5.3 Fiber Optic Probes 83
  5.4 Light Scattering 86
  5.5 Nuclear Magnetic Resonance 88
  5.6 Silicone Tubing Probes 90
  5.7 Mass Spectrometers 91
Chapter 6 — Control Systems 92
  6.1 Error Prediction 102
  6.2 Effect of Process Equipment Type 107
  6.3 Critical Loop Characteristics 108
Chapter 7 — Computer Systems 123
  7.1 FDA Audits 124
  7.2 Automated Experimentation 125
  7.3 Inferred Measurements 125
  7.4 Optimization 130
References 133
Appendix A — Continuous Biochemical Reactor Composition Control Example 137
Appendix B — ACSL Listing for Dynamic Simulation of Fermentor 141


Copyright
© Copyright 1987 Gregory K. McMillan.