Online Contents
Cover
Title
Copyright
Contents
Figures
Tables
Foreword
Acknowledgements
Chapter 1 — An Industrial Perspective
1
1.1 Products
2
1.2 Process Characteristics
8
1.3 Measurement and Control Characteristics
18
Chapter 2 — Flow, Level, Pressure, and Temperature Measurements
31
2.1 Flow Measurements
32
2.2 Level Measurements
35
2.3 Pressure Measurements
36
2.4 Temperature Measurements
36
Chapter 3 — REDOX and pH Measurements
39
3.1 REDOX Measurements
39
3.2 pH Measurement
44
3.3 Electrode Installation
60
3.4 Electrode Sterilization
62
Chapter 4 — Dissolved Oxygen and Carbon Dioxide Measurements
65
4.1 Dissolved Oxygen Measurement
66
4.2 Dissolved Carbon Dioxide Measurement
71
Chapter 5 — Composition Measurements
77
5.1 Biosensors
78
5.2 CHEMFETs and ISFETs
81
5.3 Fiber Optic Probes
83
5.4 Light Scattering
86
5.5 Nuclear Magnetic Resonance
88
5.6 Silicone Tubing Probes
90
5.7 Mass Spectrometers
91
Chapter 6 — Control Systems
92
6.1 Error Prediction
102
6.2 Effect of Process Equipment Type
107
6.3 Critical Loop Characteristics
108
Chapter 7 — Computer Systems
123
7.1 FDA Audits
124
7.2 Automated Experimentation
125
7.3 Inferred Measurements
125
7.4 Optimization
130
References
133
Appendix A — Continuous Biochemical Reactor Composition Control Example
137
Appendix B — ACSL Listing for Dynamic Simulation of Fermentor
141
Copyright
© Copyright 1987 Gregory K. McMillan.